You may need blood work done while you are taking this medication. Visit your care team for regular checks on your progress. What Should I Watch For While Using This Medication You should not take high doses of vitamin D supplements without your doctors instruction. It is also important to know the vitamin D content of other supplements you may be taking, such as a daily multivitamin. Due to the fact that vitamin D is a fat-soluble drug, the effects of vitamin D therapy can last 2 months or more after therapy is discontinued. Symptoms could include nausea, vomiting, loss of appetite, constipation, dehydration, fatigue, and confusion. These data fail to demonstrate any adverse effects of vitamin D repletion in PHPT.Vitamin D toxicity may occur with excessively high doses. Subsequently, patients with subnormal 25-OHD levels on 800 units of vitamin D daily were treated for the next 12 weeks with up to 100,000 units of vitamin D2 monthly with normalization of serum 25-OHD in all but 4 patients. None of the patients developed any calcium-related adverse events. At 10 weeks, there was a non-significant decrease in serum PTH and in urine Ca/Cr ratios. There were no significant changes in serum calcium. Patients treated with 50,000 units of vitamin D2 weekly for 8 weeks resulted in a significant increase in serum 25-OHD levels from 36.4 to 89.4 nmol/l at 5 weeks (P<0.0001) and 88.6 nmol/l at 10 weeks (P<0.0001). Serum calcium, albumin, phosphorus, 25-OHD, intact parathyroid hormone (PTH) and urine calcium/creatinine (Ca/Cr) ratios were measured before and during vitamin D therapy. Patients were treated with 50,000 units of vitamin D2 weekly for 8 weeks with biochemical measurements at 5 and 10 weeks, and subsequently after 12 weeks on 800 units of vitamin D3 daily, and in those with hypovitaminosis D after 12 weeks of up to 100 000 units of vitamin D(2) monthly. Prospective audit of the effect of vitamin D repletion on biochemical data in 56 patients with PHPT. To determine whether vitamin D repletion of patients with primary hyperparathyroidism (PHPT) and vitamin D deficiency or insufficiency (hypovitaminosis D) has deleterious clinical and/or biochemical effects.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |